First Annual Microbial Pathogenesis Symposium                            Justin Radolf, M.D., Symposium Host

                     Thursday, November 4th,  8:30 A.M. - 4:30 P.M., ARB Conference Room (EG013)

                                                                     8:00 A.M. Registration (Required) and Continental Breakfast

                                                                                           Welcome and Opening Remarks

Session I - Microbial Virulence (8:35A.M.  - 10:10 A.M)                                                                                                                                     Mary Jane Osborn, Ph.D. Host      

8:40 A.M. "Differential gene expression by Borrelia burgdorferi, the Lyme disease spirochete"  presented by Melissa Caimano, Ph.D

9:10 A.M. "Outer surface protein C of Borrelia burgdorferi:  A second generation Lyme disease vaccine candidate" presented by Steven Padula, M.D.

9:40 A.M. "DNA replication and genome maturation in Herpes Simplex Virus" presented by Sandra Weller, Ph.D.
10:10 A.M. Coffee Break
Session II - HOST-Microbial Interactions (10:25 A.M. - 12:00)                                                                                                                      Richard Zeff, Ph.D. Host

10:30 A.M. "Vaccine modification of CMV infections" presented by John Shanley, M.D.

11:00 A.M. "Bacterial lipids, periodontal disease and atherosclerosis" presented by Frank Nichols, D.D.S/Ph.D.

11:30 A.M. "Early host parasite interactions in human lymphatic filariasis" presented byThiruchandurai V. Rajan, M.D., Ph.D.
                                                                                               12:00 Noon Lunch

1:00 P.M. Afternoon remarks presented by Justin Radolf, M.D.
Session III - BIOFILM-Associated Diseases/Diseases of Mucosal Surfaces (1:05.- 2:40 P.M.)                                                                          Jason Tanzer, D.M.D.,Ph.D. Host

1:10 P.M. "Tracking mucosal immune responses in vivo" presented by Leo Lefrancois, Ph.D.

1:40 P.M."Is Streptococcus gordonii an important cariogenic microorganism? New evidence" presented by Jason Tanzer, D.M.D., Ph.D.

2:10 P.M. "Contribution of the Streptococcus mutans glucan-binding protein-A to the pathogenesis of dental caries:  The influence of biofilm on virulrnce" presented by Karsten Hazlett, Ph.D.
Session IV  - New Model Systems for Studying Microbial Pathogenesis (2:55 - 4:30 P.M.)                                                                           Ward Bullock, M.D., Host

3:00 P.M. "Early response genes in endothelial cells" presented by Timothy Hla, Ph.D.

3:30 P.M. "The human blood-brain barrier modeled in vitro:  Applications to the study of chemokines in health and disease" presnted by Joel Pachter, Ph.D.

4:00 P.M. "Old dogs, new tricks" presented by Pramod Srivastava, Ph.D.
4:30 P.M. - 6:00 P.M. Wine and Cheese Reception, ARB 7th Floor Conference Room

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